Andre Gonçalves

Andre Gonçalves

Alcohol and the brain: from genes to circuits PMC

Interestingly, activation of Midkine/Alk signaling also acts to limit alcohol intake in mice [64,65]. In contrast to Bdnf, Gdnf and Midkine, fibroblast growth factor 2 (Fgf2)/Fgf receptor 1 (Fgfr1) signaling promotes excessive drinking in rodents [66,67]. Alcohol-induced epigenetic alterations…